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Coronavirus infection of polarized epithelial cells

Identifieur interne : 001A34 ( Main/Exploration ); précédent : 001A33; suivant : 001A35

Coronavirus infection of polarized epithelial cells

Auteurs : John W. A Rossen [Pays-Bas] ; Marian C. Horzinek [Pays-Bas] ; Peter J. M Rottler [Pays-Bas]

Source :

RBID : ISTEX:E7A3EF012CF738F94D8FF92074C8ED6FD8E0F950

English descriptors

Abstract

Abstract: Epithelial cells are the first host cells to be infected by incoming coronaviruses. Recent observations in vitro show that coronaviruses are released from a specific side of these polarized cells, and this polarized release might be important for the spread of the infection in vivo. Mechanisms for the directional sorting of coronaviruses might be similar to those governing the polar release of secretory proteins.

Url:
DOI: 10.1016/S0966-842X(00)89018-6


Affiliations:


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